Major Airline Becomes First in U.S. to Launch Direct Chicago-Madrid Flights

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Major Airline Becomes First in U.S. to Launch Direct Chicago-Madrid Flights

Warm-weather enthusiasts and tapas connoisseurs, rejoice! American Airlines has officially launched its first-ever direct service from Chicago O’Hare to Madrid. On March 30, 2025, the legacy airline became the first U.S. carrier to connect these two major cities on a non-stop route. Covering roughly 4,200 miles aboard a Boeing 787-8 aircraft — which can seat up to 234 passengers — the trip takes around 8.5 hours to complete and lands you right in the heart of one of Europe’s most vibrant capitals.



Although Iberia — known as one of the best airlines in Europe — has been operating the same route for years, American’s decision to offer their own flights means the service will now be available for transatlantic travelers twice a day, which hasn’t happened since 2016. Itinerary-wise, American’s flight from Chicago O’Hare departs at 10:10 p.m. local time (arriving at 1:25 p.m. CET the next day), and with a 4:40 p.m. CET return scheduled from Madrid.

Along with expanding the options for eager travelers, this new route also joins five other American Airlines services that currently fly direct from a major U.S. airport into Madrid. Specifically, this network includes daily non-stop flights from Charlotte, Dallas/Fort Worth, Miami, New York (JFK), and Philadelphia. Better yet, the launch comes just in time for a perfect summer getaway — and to treat your inner foodie to a world-class food tour right in the Spanish capital.



Other American Airlines routes connecting Chicago to Europe

Fleet of American Airlines aircraft at Chicago O'Hare

Dave Pennells

By Dave Pennells

Dave Pennells, MS, has contributed his expertise as a career consultant and training specialist across various fields for over 15 years. At City University of Seattle, he offers personal career counseling and conducts workshops focused on practical job search techniques, resume creation, and interview skills. With a Master of Science in Counseling, Pennells specializes in career consulting, conducting career assessments, guiding career transitions, and providing outplacement services. Her professional experience spans multiple sectors, including banking, retail, airlines, non-profit organizations, and the aerospace industry. Additionally, since 2001, he has been actively involved with the Career Development Association of Australia.